FASTER PRODUCTION BUT AT WHAT PRICE?
http://esciencenews.com/articles/2009/05/04/virginia.tech.virologist.developing.more.potent.vaccine.technology
Research on creating a faster method of producing vaccines...possibly using human liver cells:
"...more motivated than ever to speed development of his cell culture-based vaccine technology that is more rapid than the egg-based growth system presently used to create vaccines"
"It also takes four to five months to prepare enough doses of the vaccine for a given year."
"The process could someday allow us to reduce the amount of time required to make flu vaccines,"
http://esciencenews.com/articles/2009/05/18/new.vaccine.strategy.might.offer.protection.against.pandemic.influenza.strains
""There is a debate in the influenza community about priming the human population for potential pandemic strains such as H5N1 or 1918," Ross said. "Some researchers advocate adding these strains to the annual flu vaccine. They might not match the next pandemic flu strain exactly, but could provide some of protection.""
http://ceoworld.biz/ceo/2009/09/03/novartis-cell-culture-based-h1n1-swine-flu-vaccine-celtura-may-work-on-fewer-doses/
Experts have predicted that two shots will be needed to provide swine flu immunity but last month China’s Sinovac Biotech, the first company worldwide to complete clinical trials for an H1N1 vaccine, said a single dose of its vaccine proved sufficient"
"Novartis is benefiting from the fact that it can produce batches of the H1N1 vaccine through a cell-based method, as opposed to a production system based on eggs. The cell-based method shortens the turnaround time to production to roughly three or four months, from six months for egg-based methods. "
CYTOKINE STORM:
http://en.wikipedia.org/wiki/Cytokine_storm
"It is believed that cytokine storms were responsible for many of the deaths during the 1918 influenza pandemic, which killed a disproportionate number of young adults.[1] In this case, a healthy immune system may have been a liability rather than an asset. Preliminary research results from Hong Kong also indicated this as the probable reason for many deaths during the SARS epidemic in 2003.[6] Human deaths from the bird flu H5N1 usually involve cytokine storms as well.[7] Recent reports of high mortality among healthy young adults in the 2009 swine flu outbreak has led to speculation that cytokine storms could be responsible for these deaths.[8] However, the Centers for Disease Control and Prevention (CDC) have indicated that symptoms reported from this strain so far are similar to those of normal seasonal flu,[9] with the CDC stating that there is "insufficient information to date about clinical complications of this variant of swine-origin influenza A (H1N1) virus infection."[9]"
http://www.cytokinestorm.com/
VIRAL SHEDDING AND THE DANGERS OF FLUMIST:
http://dprogram.net/2009/09/22/flumist-an-investigation-by-dr-sherri-tenpenny/
FOLLOW THE MONEY:
"Hundreds of TV and print advertisements have been designed to persuade everyone into taking the FluMist plunge. The campaign will be the “most intense, direct-to-consumer marketing campaign ever waged for a vaccine,” costing an estimated $25 million over the next 2.5 months [2]. In addition, Wyeth, MedImmune’s partner, plans a three-year, $100 million campaign to encourage use of the nasal flu vaccine among physicians.[3]"
And at nearly $70 a dose, this will be a financial bonanza for MedImmune and Wyeth, who are expecting the vaccine to become the blockbuster new drug that will push MedImmune’s revenues to more than $1billion/year. [5]
However, there are many reasons for caution. FluMist contains live (attenuated) influenza viruses that replicate in the nasopharynx of the vaccine recipient. The most common side effects include “cough, runny nose/nasal congestion, irritability, headaches, chills, muscle aches and fever > 100° F.”[6] These symptoms are nearly identical to those the flu vaccine is designed to prevent. [7]
A cause for significant concern is the vaccine’s most prevalent side effects: “runny nose” and “nasal congestion.” It has been documented that the live viruses from the vaccine can be shed (and potentially spread into the community) from recipient children for up to 21 days, [8] and even longer from adults.[9] Viral shedding also puts breastfeeding infants at risk if the mother has been given FluMist. [10]
In addition to shedding via nasal secretions, the virus can be dispersed through sneezing. What is the normal physiological response when an irritant enters the nasal passages? A sneeze…sometimes a big sneeze…sometimes several big sneezes. Therefore, the risk for shedding—and spreading—live viruses throughout a school, church, workplace, or store — especially one which is administering the vaccine.
In the section of the FlumMist package insert labeled “PRECAUTIONS,” the manufacturer states the following warning:
“FluMist® recipients should avoid close contact with immunocompromised individuals for at least 21 days.”
The warning is specifically directed toward those living in the same household with an immunocompromised person, but the on-going release of live viruses throughout the community may be a significant risk to everyone who has a weak, or weakened, immune system.
The number of immunocompromised people in the United States is enormous:
It is estimated that at least 10%, or more than 28 million people have eczema. [11]
More than 8.5 million people have cancer. [12]
There are reported to be 850,000 individuals with diagnosed and undiagnosed HIV infection or AIDS [13] and
Based on 2001 data, there were 184,000 organ recipients [14]
An even more extensive list of at-risk people includes the untold millions on drugs called corticosteroids. Prednisone®, Medrol®, and a variety of similar medications are given to both adults and children. These drugs are prescribed for dozens of conditions including asthma; allergies; eczema; emphysema; Crohn’s disease; multiple sclerosis; herniated spinal discs; acute muscular pain syndromes; and all types of rheumatoid and autoimmune diseases. As much as 60% of the entire population could be considered to be “chemically immunosuppressed.” It is important to realize that FluMist is CONTRAINDICATED for people who are immunocompromised. People who receive FluMist and are living with an immunocompromised person put their loved ones at risk.
http://www.rense.com/general87/flumist.htm
Liver Cells as a base for future vaccines...
http://www.articlesbase.com/medicine-articles/swine-flu-volunteers-needed-by-je-ante-1251631.html
Are Human Liver Cells safe?:
"This new swine flu H1N1 vaccine is totally new as we are now trying out for the first time human liver cell manufacturer of swine flu vaccines. For the past 60 years we have used chicken eggs but this year we are testing human liver cells for vaccine production."
What about Liver Cells from Monkeys?:
http://www.sodahead.com/living/diseased-dead-african-green-monkeys-liver-parts-used-to-make-swine-flu-vaccines-private-military-co/question-631445/
"Aside from the dangerous ingredients many people already know about (like squalene or thimerosal), one of the key ingredients used in flu vaccines (including the vaccines being prepared for the swine flu pandemic) is the diseased flesh of African Green Monkeys. This is revealed in U.S. patent No. 5911998 – Method of producing a virus vaccine from an African green monkey kidney cell line. (http://www.patentstorm.us/patents/5…)
As this patent readily explains, ingredients used in the vaccine are derived from the kidneys of African Green Monkeys who are first infected with the virus, then allowed to fester the disease, and then are killed so that their diseased organs can be used make vaccine ingredients. This is done in a cruel, inhumane “flesh factory” environment where the monkeys are subjected to a process that includes “incubating said inoculated cell line to permit proliferation of said virus.” Then: “harvesting the virus resulting from step (c); and… (ii) preparing a vaccine from the harvested virus.” "
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